GU Cancer Clinical Trials

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Subspecialty
Prostate | ON | Currently on hold
MK-5684-004
A Phase 3, Randomized, Open-label Study of MK-5684 Versus Alternative Abiraterone Acetate or Enzalutamide in Participants with Metastatic Castration-resistant Prostate Cancer (mCRPC) That Progressed On or After Prior Treatment with One Next
Mary Mahler
Start Date: September 19, 2025

NCT #: NCT6136650

SPONSOR: Merck 

INFO: https://clinicaltrials.gov/study/NCT6136650

CONTACT: Mary Mahler

905-813-1100 Ext. 5135; 

Other Canadian Centers:

1. Sunnybrook Research Institute      2. The Ottawa Hospital Cancer Centre

Prostate | ON | Recruiting
PR.26
A RANDOMIZED PHASE III CLINICAL TRIAL FOR THE ADDITION OF DOCETAXEL TO ANDROGEN RECEPTOR PATHWAY INHIBITORS IN PATIENTS WITH METASTATIC CASTRATION SENSITIVE PROSTATE CANCER AND SUBOPTIMAL PSA RESPONSE (TRIPLE-SWITCH)
Mary Mahler
Start Date: July 2, 2025

NCT #: NCT06592924

SPONSOR: Canadian Cancer Trials Group - CCTG

INFO: https://clinicaltrials.gov/study/NCT06592924

CONTACT: Mary Mahler

905-813-1100 Ext. 5135

Other Canadian Centers:

1. The Ottawa Hospital Cancer Centre 2. Juravinski Cancer Centre 3. Niagara Health System 4. Brampton Civic Hospital (WOHS) 5. Sunnybrook Health Sciences Centre 6. Health Sciences North/Horizon Santé-Nord 7. Verspeeten Family Cancer Centre (LHSCRI) 8. Kingston General Hospital

Prostate | QC | Not yet recruiting
190211_1
A SMART Design to Optimize the Delivery of TEMPO for Men With Prostate Cancer and Their Caregivers
Sylvie Lambert
Start Date: September 1, 2024

NCT #: NCT06363266

SPONSOR: St. Mary's Research Center, Canada

INFO: https://clinicaltrials.gov/study/NCT06363266

CONTACT: Sylvie Lambert

514-398-3685; sylvie.lambert@mcgill.ca

Other Canadian Centers:

1. St. Mary's Hospital Research Centre (Montreal)

Prostate | ON | Recruiting
PR.24
ANDROGEN SUPPRESSION COMBINED WITH ELECTIVE NODAL IRRADIATION AND DOSE ESCALATED PROSTATE TREATMENT: A NON-INFERIORITY, PHASE III
Jasper Yuen
Start Date: August 20, 2024

NCT #: NCT06235697

SPONSOR: Canadian Cancer Trials Group - CCTG

INFO: https://clinicaltrials.gov/study/NCT06235697

CONTACT:  Jasper Yuen

905-813-1100 ext. 3068; 

Other Canadian Centers:
1. London Regional Cancer Centre ( London, Ontario) 2. Royal Victoria Regional Health Centre-(Barrie, Ontario) 3.Grand River Cancer Center (Kitchener, Ontario) 4. Health Sciences North Sudbury (Sudbury, Ontario)

Prostate | BC | Not yet recruiting
H20-02418
Dynamic Whole Body PET/​ MRI
Start Date: August 1, 2024

NCT #: NCT04495959

SPONSOR: British Columbia Cancer Agency

INFO: https://clinicaltrials.gov/study/NCT04495959

CONTACT: Heather Saprunoff 

hsaprunoff@bccancer.bc.ca; 604-877-6000 x 2818

Other Canadian Centres:

1. BC Cancer (Vancouver)

Prostate | ON | Not yet recruiting
SChLAP/IDC Study
Study of Radiation Therapy in Combination With Darolutamide + Degarelix in Intermediate Risk Prostate Cancer (SChLAP/IDC)
Start Date: July 2, 2024

NCT #: NCT04176081

SPONSOR: University Health Network

INFO: https://clinicaltrials.gov/study/NCT04176081

CONTACT: Sunakshi Chowdhary

Sunakshi.Chowdhary@uhn.ca; 416-946-4501 x 5836

Other Canadian Centres:

1. Princess Margaret Hospital (Toronto)

Prostate | ON | Not yet recruiting
dualPET-mPC
Dual PSMA and FDG PET Imaging for Patients With Advanced Prostate Cancer
Di (Maria) Jiang
Start Date: June 1, 2024

NCT #: NCT06335914

SPONSOR: University Health Network

INFO: https://clinicaltrials.gov/study/NCT06335914

CONTACT: Di (Maria) Jiang

416-946-4501 x 4807; di.jiang@uhn.ca

Other Canadian Centres:

1. Princess Margaret Hospital (Toronto)

Renal | ON | Not yet recruiting
4722
Obesity Management for Kidney TRANSPLANTation: OK-TRANSPLANT 2
Kristin K Clemens, Louise Moist
Start Date: June 1, 2024

NCT #: NCT06396416

SPONSOR: Western University

INFO: https://clinicaltrials.gov/study/NCT06396416

CONTACT: heather.lapier@sjhc.london.on.ca

Other Canadian Centres:

1. London Health Sciences Centre (London)

Renal | BC | Recruiting
ADVANTage, DAIT CTOT-41
Advancing Transplantation Outcomes in Children (ADVANTage)
David Briscoe, Eileen Chambers
Start Date: May 24, 2024

NCT #: NCT06055608

SPONSOR: National Institute of Allergy and Infectious Diseases (NIAID)

INFO: https://clinicaltrials.gov/study/NCT06055608

CONTACT: Monica Ho (Vancouver): 604-875-2000 x 2485                

Monica.Ho@bcchr.ca

Other Canadian Centres:

1. British Columbia Children's Hospital (Vancouver)

Renal | ON | Not yet recruiting
22-6002
EASE-SOT Pilot Study
Istvan Mucsi
Start Date: May 1, 2024

NCT #: NCT06396702

SPONSOR: University Health Network, Toronto

INFO: https://clinicaltrials.gov/study/NCT06396702

CONTACT: Istvan Mucsi: istvan.mucsi@utoronto.ca                      

416-659-6756

Other Canadian Centres:

1. Toronto General Hospital (Toronto)

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